Phenylcarbamic acid esters

Organic compounds that consist of a phenylcarbamic acid where the hydrogen atom bonded to the oxygen atom is replaced with an organic group; phenylcarbamic acid a carboxylic acid bonded to an amino group with a phenyl group substitution.

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826

Medchemexpress LLC 4,7,10,14-tetraoxahexadecanoic acid, 15,15-dimethyl-13-oxo- | 1807539-06-5 | >=97.0% | 250 MG

Acid-PEG3-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker, with a molecular weight of 306.35 and chemical formula C14H26O7. It appears as a colorless to light yellow liquid and is for research use only. The pure form should be stored at -20°C for 3 years or 4°C for 2 years, while in solvent, it should be stored at -80°C for 6 months or -20°C for 1 month. It is soluble in DMSO at concentrations of 175 mg/mL (571.24 mM) or greater. This product is utilized in the synthesis of PROTACs.

Can be used in the synthesis of PROTACs for the degradation of EGFR.
Inhibits mTOR.
Utilizes the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Contains two different ligands connected by a linker; one for an E3 ubiquitin ligase and the other for the target protein.